Mercury, mercurials, and mercaptans.

  • 386 Pages
  • 4.49 MB
  • English
Thomas , Springfield, Ill
Mercury -- Toxicology -- Congresses., Mercury -- Metabolism -- Congresses., Thiols -- Congre
StatementEdited by Morton W. Miller [and] Thomas W. Clarkson.
ContributionsMiller, Morton W., 1936- ed., Clarkson, Thomas W., ed., University of Rochester. Dept. of Radiation Biology and Biophysics.
LC ClassificationsRA1231.M5 R56 1971
The Physical Object
Paginationxvii, 386 p.
ID Numbers
Open LibraryOL5300566M
ISBN 100398026009
LC Control Number72081709

COVID Resources. Reliable information about the coronavirus (COVID) is available from the World Health Organization (current situation, international travel).Numerous and frequently-updated resource results are available Mercury this ’s WebJunction has pulled together information and resources to assist library staff as they consider how to handle.

Since nonchelated mercury(II)—thiol compounds did not show synergism, the formation of very high affinity bidentate chelates appears to be essential for such synergism. A major mechanism for the augmentation of the inducer potency of mercury(II) by BAL is the more rapid cellular uptake and the accumulation of higher intracellular Cited by: Reactions of Thiols with Organic Mercury Compounds1 Reinhold Benesch and Ruth E.

mercurials Benesch From the Department of Biochemistry, Northwestern University Medical School, Chicago, Illinois Received Febru INTRODUCTION One of the most characteristic properties of mercaptans is their reaction with heavy metals to form stable by: Mercury's high affinity for thiol ligands presents a challenge to enzymes that use iron-sulfur clusters [50, 85].

coli's labile iron pool is approximately µM and exposure to HgCl 2 at a fold molar excess over cellular thiols can release as. Mercury occurs widely in the biosphere. It is a toxic element that presents occupational hazards associated with both ingestion and inhalation.

It is used. TOXICOLOGY AND APPLIED PHARMACOL () Effects of Coadministered Low-Molecular-Weight Thiol Compounds on Short-Term Distribution of Methyl Mercury in the Rat' DAVID J. THOMAS2 AND J. CRISPIN SMITH 3 Environmental Health Sciences Center and Department of Pharmacology and Toxicology, University of Rochester Cited by: Mercuric mercury also forms a number of organo-metal1ic compounds.

The short-chain alkyl mercurials, e.g., methylmercury (MeHg) compounds, possess high stability and unique toxicologic properties. Other classes of organomercurials such as phenyl mercury compounds are highly unstable in mammalian tissues, rapidly breaking down to inorganic mercury.

The development of the environmental mercury problem and the toxicity of mercury and its compounds have received attention in numerous recent reviews (27, 28, 29, Abstract. Intoxication by elemental mercury or by methylmercury is revealed primarily by changes in behavior and by neurological signs.

Disorders of movement and posture have been most widely reported, both in animal experiments and in cases of human exposure.

The extent of mercury binding by the chromatin of kidneys and liver of rats exposed to HgCl 2 (20 mg Hg/kg body wt; single intravenous injection) was investigated.

A considerable accumulation of this metal into cell nuclei of both the examined organs was observed ( and μg Hg/mg protein, respectively). Experiments were conducted to ascertain if exposure of goldfish (Carassius auratus) to l-cysteine, l-glutathione, calcium pantothenate, pantethine, or.

Mercury poisoning has become a problem of current interest as a result of environmental pollution on a global scale. Natural emissions of mercury form two-thirds of the input; manmade releases form about one-third. Considerable amounts of mercury may be added to agricultural land with sludge, fertilizers, lime, and manures.

The most important sources of contaminating. Inorganica Chimica Acta, 92 () Metal-Penicillamine Interactions. Part 1. Preparation and Crystal Structure of a Complex of Mercuric Chloride with D-Penicillamine, 2 [ (3 -Cl){HgSC(CH3)2 CH(NH3)C ] 3(;i 2-C1)' 2(H30) (H20C1)3 LANGFORD BOOK Department of Chemistry, Nankai University, Tianjin, China and THOMAS C.


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Segments were perfused in situ for i0 min at ml/min with saline containing 20 ~M Cd and Hg; perfusion continued for I0 min with saline 1 mM GSH. Vol. 52, No. 20, Metal Trapping and Thiol Compounds When, as in table II, uptake and extrusion were both determined in presence of GSH, the thiol compound exerted no significant effect on.

Mercury, mercurials, and mercaptans. Morton W. Miller and Thomas W. Clarkson. Published by Thomas. ISBN ISBN by Schamberg, Morton Livingston & Frederick Thomas Bigger &James Bullen Karcher (illustrator).

Revised Edition. Book cover has a couple small stains and is worn at ends of spine and corner edges. Mercury toxicity. Mercury (Hg) is a ubiquitous environmental pollutant to which humans are exposed to in varying amounts and chemical forms (Clarkson and Magos, ).The three main forms of Hg that are a cause of concern to non-occupationally exposed human populations include methylmercury (MeHg), mercury vapor (Hg 0) and ethylmercury (EtHg) (Clarkson et.

There is also an introduction which discusses what mercury toxicity is all about. Even if you can gorge on high-thiol foods and nothing happens, this book is a really interesting read." Rebecca Rust Lee- co-author with Dr Andrew Hall Cutler The Mercury Detoxification Manual: a guide to mercury chelation.

Mercurial diuretics such as mersalyl acid were once in common use, but have been superseded by the thiazides and loop diuretics, which are safer and longer-acting, as well as being orally active.

Thiol affinity chromatography. Thiols are also known as mercaptans due to their propensity for mercury tes (R-S −) and thioketones (R 2 C=S), being soft. Mercury in Man.

Mercury Mercurials and. Mercaptans, ed. by M.W Miller, and. Mercury is a ubiquitous environmental toxin that can produce a.

The capacity for blocking essential thiol groups in cellular enzymes and membranes leads to neurotoxic effects of mercurials (Syversen and Kaur, ).

Analogs mechanisms also contribute to the toxicity of other thiophilic metals, e.g., arsenic (As), Pb, and Cu (Aaseth et al., a). Mercury is a metal that exists in the environment in three forms, namely, elemental mercury (Hg°), inorganic mercury salts (Hg + and Hg 2+), and organic mercurials (e.g., dimethyl mercury).

When animals or humans are exposed to Hg°, it is rapidly oxidized in the body to Hg +. Hence, only inorganic mercury salts and organic mercurials are. Rothstein A () Mercaptans, the biological targets for mercurials. In: Miller M, Clarkson M (eds) Mercury, Mercurials and Mercaptans.

Thomas, Springfield, pp 38– Google Scholar; Siegel SM, Eshleman A, Umeno I, Purnmer N, Smith CW () The general and comparative biology of toxic metals and their derivatives: Mercury and lead.

Immunization to protect infants and children from vaccine-preventable diseases is one of the greatest achievements in public health. The use of vaccines is not without risks, however.

It is well established, for example, that vaccines sometimes cause anaphylactic shock, and that the oral polio vaccine can on rare occasions cause paralytic polio. Given the widespread use of. Europe PMC is an archive of life sciences journal literature.

Abstract. (+)-Penicillamine in a dose of μmoles/kg given subcutaneously twice a day on the sixth and seventh days after the administration of μg mercury increased the urinary excretion of rats more than the equimolar dose of N-acetyl-(+)-penicillamine but less than 2,3-dimercaptopropanol μmoles/kg.

After thiol functionalization, the material had a pore size of nm, a BET surface area of m 2 /g, and a silane population of thiol silanes/nm 2 (determined using thermogravimetric analyzer, NETZCH STA C/CD TGA).

This high level of coverage forces the propyl chains into an upright posture, and forces the thiols up to the monolayer. J Biol Inorg Chem. Dec;20(8) doi: /s Epub Oct Organic and inorganic mercurials have distinct effects on cellular thiols, metal homeostasis, and Fe-binding proteins in Escherichia coli.

Mercurials were native to the planet Mercury. Biogology Edit. Mercurials were tall, humanoid, and smooth and arms ended in points and their feet ended in flat discs. (PROSE: Mercury) History Edit. Soon after the Sunwatcher project was set up on Mercury by Earth humans, the Mercurials were attacked by "giants".One of the Mercurials was found and.

Description Mercury, mercurials, and mercaptans. EPUB

In: Miller MW, Clarkson TW, eds. Mercury, Mercurials, and Mercaptans. Springfield, Ill: Charles C Thomas Publishing Co; Sherlock J, Hisplop J, Newton D. et al. Elevation of mercury in human blood from controlled chronic ingestion of methylmercury in fish.

Hum. Department of Radiation Biology and Biophysics. Title(s): Mercury, mercurials and mercaptans, edited by Morton W. Miller [and] Thomas W. Clarkson. Country of Publication: United States Publisher: Springfield, Ill., Thomas [c] Description: xvii, p.

ill. Language: English ISBN:LCCN: MeSH: Mercury.

Details Mercury, mercurials, and mercaptans. EPUB

Mercury in the environment accumulates both naturally and because of industrial practices that began in the first half of the 20th century. Although most of the mercury becomes deposited in soils bound to clay particles or organic compounds (), a significant amount enters aquatic food chains ().Mercury (Hg II) carried by rainfall is the main source for this heavy metal in areas not.

Mercury's high affinity for thiol ligands presents a challenge to enzymes that use iron-sulfur clusters [50, 85]. 's labile iron pool is approximately µM.‘The Ascendant to quintile Mercury suggests that he ‘should now have rectified his books of accounts and receive much benefit from Mercurial men’.’ ‘The odour of Mercurial herbs is described as ‘highly subtle and penetrating, refreshing to the heart and brain.’’ ‘Modern authors also note the Mercurial influence.’.Mercury herb is a plant.

People use the flowering plant, root, and root-like stem (rhizome) of the plant to make medicine. Despite serious safety concerns, mercury herb is used for treating.